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Ablation beats drug remedy for ladies and men with A-fib


(HealthDay)—For sufferers with atrial fibrillation (AF), these present process ablation have a considerably decreased threat for recurrent AF in contrast with these receiving drug remedy, no matter intercourse, in line with a examine revealed within the Feb. 16 situation of Circulation.

Andrea M. Russo, M.D., from Cooper Medical Faculty of Rowan College in Camden, New Jersey, and colleagues examined outcomes for 819 girls and 1,385 males with AF ages 65 years and older or aged youthful than 65 years with at the very least one threat issue for stroke. Contributors have been randomly assigned to both catheter ablation with pulmonary vein isolation or drug remedy with fee/rhythm management brokers.

The researchers discovered that through the index process, girls have been much less possible than males to have ancillary ablation procedures carried out (55.7 versus 62.2 p.c); in each sexes, problems from remedy occurred occasionally. For the first consequence of demise, disabling stroke, severe bleeding, or cardiac arrest, the hazard ratio was 1.01 (95 p.c confidence interval, 0.62 to 1.65) for girls and 0.73 (95 p.c confidence interval, 0.51 to 1.05) for males for ablation versus drug remedy. In contrast with these receiving drug remedy, sufferers present process ablation had a considerably decreased threat for recurrent AF, however the impact was higher for males (hazard ratio, 0.48; 95 p.c confidence interval, 0.40 to 0.58) than girls (hazard ratio, 0.64; 95 p.c confidence interval, 0.51 to 0.82).

“When compared with drug therapy, ablation offers comparable benefits for women and men,” the authors write. “Consequently, sex should not be used as a basis for selecting a management strategy for the treatment of AF.”

A number of authors disclosed monetary ties to pharmaceutical and medical machine firms, a few of which funded the examine.


Ablation cuts threat of recurrent stroke in sufferers with A-fib


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retrieved 16 February 2021
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