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Drop in PSA screening linked to extend in metastatic prostate most cancers


(HealthDay)—Reductions in prostate-specific antigen (PSA) screening are related to will increase within the incidence of metastatic prostate most cancers at analysis, based on a research offered on the American Society of Scientific Oncology annual Genitourinary Cancers Symposium, held nearly from Feb. 11 to 13.

Vidit Sharma, M.D., from the College of California Los Angeles, and colleagues examined longitudinal variations in PSA screening and their associations with the incidence of metastatic prostate most cancers at analysis throughout particular person states from 2002 to 2016.

The researchers discovered that the p.c of males older than 40 years who reported ever receiving PSA screening diversified considerably between states (vary, 40.1 to 70.3 p.c), as did the age-adjusted incidence of metastatic prostate most cancers at analysis (vary, 3.3 to 14.3 per 100,000). The imply share of males screened decreased from 61.8 to 50.5 p.c from 2008 to 2016, whereas the imply incidence of metastatic prostate most cancers at analysis elevated (6.4 to 9.0 per 100,000). There was an affiliation famous between longitudinal reductions throughout states in PSA screening and elevated metastatic prostate most cancers (regression coefficient per 100,000 males, 14.9). Bigger will increase within the incidence of metastatic prostate most cancers at analysis have been seen in states with bigger reductions in PSA screening. Twenty-seven p.c of the longitudinal variation in metastatic prostate most cancers inside states was defined by variation in PSA screening.

“The magnitude of decreased PSA screening was correlated to the magnitude of increased metastatic disease, suggesting that there may be a link at population level,” Sharma stated in a press release.


U.S. incidence of distant-stage prostate most cancers up, 2010 to 2017


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Drop in PSA screening linked to extend in metastatic prostate most cancers (2021, February 16)
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